Maura Boldrini, MD, PhD is a Professor of Psychiatry, Director of the Quantitative Brain Biology (Brain QUANT) Institute, and the Human Neurobiology laboratory in the Department of Psychiatry at the Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, and the New York State Psychiatric Institute. Her research focuses on understanding underlying mechanisms of behavioral, cognitive, and emotional changes associated with brain diseases.

In her laboratory, Dr. Boldrini is studying brain circuits at the cellular and molecular level, and she is interested in understanding how the mind and the brain interact generating symptoms that make people suffer. She has extensively studied neuron re-growth in the brain and has shown that the human brain can make new neurons throughout our lifetime. Neuron regeneration is learning and memory, copying with stress, healthy aging, and mental health. For the past few years, she has also been studying how neuroinflammation and COVID-19 affect brain function.

Her lab is applying single-cell and spatial multiomic technologies to identify transcriptome, epigenome and proteome biosignatures of human brain cell function and state regulation.

Her team has been implementing computational methods for analyzing gene regulatory networks and generating extensive multiome datasets that are an extremely valuable resource for the scientific community.

Dr. Boldrini is mentoring predoctoral and postdoctoral fellows, including bioengineering and data sciences students and postdocs. She is trained on Culturally Aware Mentoring and is passionate and dedicated to providing equal opportunities to trainees of all backgrounds, offering guidance, networking, and skill development necessary for their success.